Popović A: Metastatic renal cell carcinoma

SUMMARY · Renal cell carcinoma is the third leading urologic cancer. Thirty percent of patients with renal cell carcinoma have metastatic disease at the time of diagnosis. The most frequent loca-tions of metastases from renal cell carcinoma are the lungs, mediastinum, bone, liver, and brain. There are several treatment modifications for metastatic renal cell carcinoma, with varying results. Surgical therapy is contraindicated in patients with multiple metastases, due to poor survival. Relief of pain and other symptoms poses a serious problem in patients with metastases