Add to ORKGPart of the Biochemistry, Biophysics, and Structural Biology Commons This Article is brought to you for free and open access by the Molecular and Cellular Biochemistry at UKnowledge. It has been accepted for inclusion in Molecular and Cellular Biochemistry Faculty Publication by an authorized administrator of UKnowledge. For more information, please contac
<p>HEK293T cells were transiently transfected (100 nM) with either control siRNA (siRNA-Control) or ...
<p><b>A</b>, HeLa cells were transfected with YFP-H-RAS (N17S), serum-starved and then incubated wit...
Signaling scaffolds are critical for the correct spatial organization of enzymes within the ERK1/2 s...
<div><p>Shoc2 is the putative scaffold protein that interacts with RAS and RAF, and positively regul...
Shoc2 is the putative scaffold protein that interacts with RAS and RAF, and positively regulates sig...
<div><p>Shoc2 is a positive regulator of signaling to extracellular signal-regulated protein kinases...
<p><b><i>A,</i></b> Parental Cos1 and Cos1 cells stably expressing Shoc2-shRNA (Cos-LV1) or Shoc2-sh...
Shoc2 is a positive regulator of signaling to extracellular signal-regulated protein kinases 1 and 2...
<p><b>A</b>, Parental Cos1 and Cos1 cells stably expressing Shoc2-shRNA (Cos1-LV1) were serum-starve...
The extracellular signal-regulated kinase (ERK1/2) cascade regulates a myriad of functions in multic...
The Shoc2 protein has been implicated in the positive regulation of the Ras-ERK pathway by increasin...
<p><b>A</b>, HeLa cells were transfected with CHC or non-targeting (NT2) siRNAs and serum-starved. T...
<p><b>A</b>), PC12 cells were co-transfected with plasmids pCEFL-KZ-GFP (0.3 µg) and pCEFL-KZ-AU5 (0...
<p><b><i>A</i></b>, Cos-LV1 cells were transiently transfected with full-length Shoc2-tRFP or Shoc2-...
SHOC2 is mutated in Noonan syndrome and plays a key role in the activation of the RAS-ERK pathway, ...
<p>HEK293T cells were transiently transfected (100 nM) with either control siRNA (siRNA-Control) or ...
<p><b>A</b>, HeLa cells were transfected with YFP-H-RAS (N17S), serum-starved and then incubated wit...
Signaling scaffolds are critical for the correct spatial organization of enzymes within the ERK1/2 s...
<div><p>Shoc2 is the putative scaffold protein that interacts with RAS and RAF, and positively regul...
Shoc2 is the putative scaffold protein that interacts with RAS and RAF, and positively regulates sig...
<div><p>Shoc2 is a positive regulator of signaling to extracellular signal-regulated protein kinases...
<p><b><i>A,</i></b> Parental Cos1 and Cos1 cells stably expressing Shoc2-shRNA (Cos-LV1) or Shoc2-sh...
Shoc2 is a positive regulator of signaling to extracellular signal-regulated protein kinases 1 and 2...
<p><b>A</b>, Parental Cos1 and Cos1 cells stably expressing Shoc2-shRNA (Cos1-LV1) were serum-starve...
The extracellular signal-regulated kinase (ERK1/2) cascade regulates a myriad of functions in multic...
The Shoc2 protein has been implicated in the positive regulation of the Ras-ERK pathway by increasin...
<p><b>A</b>, HeLa cells were transfected with CHC or non-targeting (NT2) siRNAs and serum-starved. T...
<p><b>A</b>), PC12 cells were co-transfected with plasmids pCEFL-KZ-GFP (0.3 µg) and pCEFL-KZ-AU5 (0...
<p><b><i>A</i></b>, Cos-LV1 cells were transiently transfected with full-length Shoc2-tRFP or Shoc2-...
SHOC2 is mutated in Noonan syndrome and plays a key role in the activation of the RAS-ERK pathway, ...
<p>HEK293T cells were transiently transfected (100 nM) with either control siRNA (siRNA-Control) or ...
<p><b>A</b>, HeLa cells were transfected with YFP-H-RAS (N17S), serum-starved and then incubated wit...
Signaling scaffolds are critical for the correct spatial organization of enzymes within the ERK1/2 s...