Research Article Telomerase as an Important Target of Blockade for Prostate Cancer Treatm

As the mainstay treatment for advanced prostate cance action of androgen receptor (AR) by reducing androgen le androgens for binding to AR. Albeit effective in extendi toxicity and the development of castration-resistant pro CRPC is lethal and incurable, developing effective strateg resistance becomes an urgent task. Continuous AR signali development of CRPC. The present study showed that m reduces AR abundance, could enhance the cancer-killi at the and a ase. T f the ifican i-and role