Printed in U.S.A. Approaches to the Study of Amino Acid Requirements in Uremia

tein restriction in patients with renal insufficiency (1) suggest time need for a precise definition of the amino acid re-quirements for tlmesc individuals. It would seem that the dietary amino acid intake with adequate calorie support should be adjusted so that the tissue use of amino acids for protein synthesis is promoted to time greatest degree while the catabolism of amino acids is kept at a minimum. Protein or anmino acid requirements can now be defined in terms of adequate anmounts, in time duet, of the eight or nine essential amino acids supplemented with additional amino acids to provide for tim