Atherothrombotic disorders: new insights from hematology. Circulation

How should we address the increasingly prevalent condi-tion of arterial thrombophilia? Can arterial thromboses complicate hematological diseases or the use of antithrom-botic drugs? What is POC testing? Is vascular regeneration a potential shield against atherothrombotic states? This report draws insights and perspective from the discipline of hema-tology to answer these and other clinically relevant questions. Thrombophilias and Their Evaluation The term thrombophilia can be applied to both inherited and acquired disorders that predispose to thrombosis; the 2 forms, inherited and acquired, may coexist within the same individ-ual. Although best characterized in the context of venous thromboembolism, the contribution of thrombophilias to arterial thrombosis is an area of intense investigation (Table). Inherited Disorders of the Hemostatic System Predisposing to Arterial Thrombosi