Journal of Biotechnology, Computational Biology and Bionanotechnology REVIEW PAPER Survival in extremes

Demand is growing for extremozymes for biotechnological purposes. Extremophilic organisms are a natural source of enzymes that possess features desired by the biotechnology and medical industries. X-ray crystallo-graphy can reveal the nature of enzyme adaptation strategies to extreme environments. Biotechnological aspects of temperature adaptation Ever since our ancestors made their first simple tools, mankind has continually been looking for new ma-terials from the natural environment to overcome life’s obstacles and to thrive. Today, our knowledge about the world around us has extended to the molecular scale as a result of the advent of the age of molecular biology. This has enabled us to gain insight into molecular me-chanisms and even to describe the spacial arrangement of atoms in bio-molecules, which promises application