Meningitis associated with Vancomycin resistant Enterococcus casseliflavus:

Enterococci are present in the gastrointestinal system as normal floral components. In the past two decades members of the genus Enterococcus have emerged as important nosocomial pathogens worldwide. Enterococci may cause a range of different disorders such as urinary tract, intraabdominal, and wound infections, as well as endocarditis, menin-gitis and bacteraemia. Nosocomial enterococcal meningitis is most commonly observed following ventriculoperitoneal shunt operations. Vancomycin resistant enterococcus (VRE) represents 30 % of all enterococci infections. This report presents a vancomycin-resistant Enterococcus casseliflavus meningitis case in a 66-year-old patient with ventriculoperitoneal shunt, which has not been reported in the literature before. Successful outcomes were obtained with daptomycin plus linezolid combined treatment in VRE meningitis. Treatment recommendations in VRE meningitis are also discussed in this article. J Microbiol Infect Dis 2011;1 (3):138-14