Add to ORKGABSTRACT: 2,4-Dichloro-pyrimidine-6-carbonylchloride (2) was synthesized by refluxing orotic acid (1) with phosphorus oxychloride and phosphorus pentachloride. Compound (2) underwent a smooth Friedel-Craft's reaction with a number of substituted benzene to yield 2,4-Dichloro-6-aroylpyrimidines 6 and 7 which were converted to the corresponding dimethoxy pyrimidines (8, 9) on treatment with sodium methoxide in methanol. The iodination reaction on 2,4-dimethoxy-6-aroylpyrimidines (8, 9) was attempted by several methods but only NIS-TFA-TFAA method gave the desired products, 2,4-dimethoxy-5-iodo-6-aroylpyrimidine (10, 11) in good yields
Eco-friendly one-pot synthesis of new 6-iodo-4H-pyrano[2,3-d]pyrimidin-4-ones via the condensation o...
Reaction of 5'-O-(4,4'-dimethoxytriphenylmethyl)-3'-deoxythymidine with triphenylphosphine/carbon te...
The synthesis of 2,4,6-tris(4-N-isopropylamidinophenyl)pyrimidine from 1,3-di(4-bromophenyl)propen-3...
The reaction of benzylhydroxylamine with 6-cyanopurines leads to the formation of 7-benzyloxy-8-imin...
A simple, high yield synthesis of thymidine from 5-iodo-2'-deoxyuridine is described, using tetramet...
Department of Chemical Technology, University Colleges of Science and Technology, University of Calc...
A Brønsted acid-catalyzed reaction of 6-amino uracil and isatin-derived propargylic alcohols for the...
Synthesis of some 2,4-diamino-6-(substituted amino)-, 2,4-dibydroxy-6-(substituted amino)-, 2- amino...
The effect of the tertiary amines triethyl, tri-n-propyl, and tri-n-butylamines on the chlorination ...
5-Pyrimidyllithium species are fairly stable when the metal is flanked by two electron-withdrawing s...
In this paper the solid phase synthesis of various substituted purines is described starting from 4,...
In this paper the solid phase synthesis of various substituted purines is described starting from 4,...
In this paper the solid phase synthesis of various substituted purines is described starting from 4,...
<p>Conditions: (a) TEA, EtOH, reflux, 2.5 h, 31%; (b) POBr<sub>3</sub>, DMF, MW 90 °C, 10 min, 75%; ...
ABSTRACT: The objective of present research work is to provide green technique for synthesis of 4-(4...
Eco-friendly one-pot synthesis of new 6-iodo-4H-pyrano[2,3-d]pyrimidin-4-ones via the condensation o...
Reaction of 5'-O-(4,4'-dimethoxytriphenylmethyl)-3'-deoxythymidine with triphenylphosphine/carbon te...
The synthesis of 2,4,6-tris(4-N-isopropylamidinophenyl)pyrimidine from 1,3-di(4-bromophenyl)propen-3...
The reaction of benzylhydroxylamine with 6-cyanopurines leads to the formation of 7-benzyloxy-8-imin...
A simple, high yield synthesis of thymidine from 5-iodo-2'-deoxyuridine is described, using tetramet...
Department of Chemical Technology, University Colleges of Science and Technology, University of Calc...
A Brønsted acid-catalyzed reaction of 6-amino uracil and isatin-derived propargylic alcohols for the...
Synthesis of some 2,4-diamino-6-(substituted amino)-, 2,4-dibydroxy-6-(substituted amino)-, 2- amino...
The effect of the tertiary amines triethyl, tri-n-propyl, and tri-n-butylamines on the chlorination ...
5-Pyrimidyllithium species are fairly stable when the metal is flanked by two electron-withdrawing s...
In this paper the solid phase synthesis of various substituted purines is described starting from 4,...
In this paper the solid phase synthesis of various substituted purines is described starting from 4,...
In this paper the solid phase synthesis of various substituted purines is described starting from 4,...
<p>Conditions: (a) TEA, EtOH, reflux, 2.5 h, 31%; (b) POBr<sub>3</sub>, DMF, MW 90 °C, 10 min, 75%; ...
ABSTRACT: The objective of present research work is to provide green technique for synthesis of 4-(4...
Eco-friendly one-pot synthesis of new 6-iodo-4H-pyrano[2,3-d]pyrimidin-4-ones via the condensation o...
Reaction of 5'-O-(4,4'-dimethoxytriphenylmethyl)-3'-deoxythymidine with triphenylphosphine/carbon te...
The synthesis of 2,4,6-tris(4-N-isopropylamidinophenyl)pyrimidine from 1,3-di(4-bromophenyl)propen-3...