Insulin-like growth factors (IGF) have been associated with risk of common human cancers, but the associa-tion between IGFs and pancreatic cancer risk is unclear. To determine whether genetic variations of IGF modify pancreatic cancer risk, we compared the frequency of six single nucleotide polymorphisms of IGF1 and IGF2 in a large-scale case control study. Single nucleotide polymorphisms were investigated using the TaqMan method in 892 patients with pancreatic ductal adenocar-cinoma and 783 healthy controls who were recruite
Breast cancer is the most common cancer worldwide with significant global burden. Insulin-like growt...
Obesity and diabetes are major modifiable risk factors for pancreatic cancer. Interactions between g...
Insulin-like growth factor (IGF) 1 and its binding proteins foster cellular proliferation and inhibi...
Abstract Background Many epidemiological studies have suggested that insulin-like growth factor1 (IG...
Background and Aims—Insulin-like growth factor (IGF)-axis mediated signaling pathways play an import...
Insulin-like growth factor I (IGF-I) stimulates cell proliferation and can enhance the development o...
Insulin-like growth factor I (IGF-I) stimulates cell proliferation and can enhance the development o...
Insulin-like growth factor I (IGF-I) is an important regu-lator of growth and differentiation and is...
Insulin-like growth factor I (IGF-1) stimulates cell proliferation and can enhance the development o...
Although type 2 diabetes mellitus is a known risk factor for pancreatic cancer, the existence of sha...
Insulin-like growth factor-1 (IGF-I), a potent mitogen, is hypothesized to influence breast cancer r...
Insulin-like growth factor-1 (IGF-1) is involved in several processes relevant to carcinogenesis. We...
Pancreatic ductal adenocarcinoma (PDAC), which represent the 95% of all the pancreatic cancers, is o...
Abstract Background The rs1520220 polymorphism in the insulin-like growth factor 1 (IGF1) gene has b...
Interrelationships between insulin-like growth factors (IGFs), hyperinsulinaemia, diabetes, and colo...
Breast cancer is the most common cancer worldwide with significant global burden. Insulin-like growt...
Obesity and diabetes are major modifiable risk factors for pancreatic cancer. Interactions between g...
Insulin-like growth factor (IGF) 1 and its binding proteins foster cellular proliferation and inhibi...
Abstract Background Many epidemiological studies have suggested that insulin-like growth factor1 (IG...
Background and Aims—Insulin-like growth factor (IGF)-axis mediated signaling pathways play an import...
Insulin-like growth factor I (IGF-I) stimulates cell proliferation and can enhance the development o...
Insulin-like growth factor I (IGF-I) stimulates cell proliferation and can enhance the development o...
Insulin-like growth factor I (IGF-I) is an important regu-lator of growth and differentiation and is...
Insulin-like growth factor I (IGF-1) stimulates cell proliferation and can enhance the development o...
Although type 2 diabetes mellitus is a known risk factor for pancreatic cancer, the existence of sha...
Insulin-like growth factor-1 (IGF-I), a potent mitogen, is hypothesized to influence breast cancer r...
Insulin-like growth factor-1 (IGF-1) is involved in several processes relevant to carcinogenesis. We...
Pancreatic ductal adenocarcinoma (PDAC), which represent the 95% of all the pancreatic cancers, is o...
Abstract Background The rs1520220 polymorphism in the insulin-like growth factor 1 (IGF1) gene has b...
Interrelationships between insulin-like growth factors (IGFs), hyperinsulinaemia, diabetes, and colo...
Breast cancer is the most common cancer worldwide with significant global burden. Insulin-like growt...
Obesity and diabetes are major modifiable risk factors for pancreatic cancer. Interactions between g...
Insulin-like growth factor (IGF) 1 and its binding proteins foster cellular proliferation and inhibi...