Bcl-XL is a dominant antiapoptotic protein which inhibits homoharringtonine-induced apoptosis in leukemia cells
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
Interactions between the pro-survival and pro-apoptotic members of the Bcl-2 family of proteins dict...
Overexpression of two antiapoptotic proteins — Bcl-2 and Bcl-X L — is commonly observed in many canc...
Homoharringtonine (HHT) has been reported to be effective in a portion of patients with acute myeloi...
SummaryCancer cells hijack BCL-2 family survival proteins to suppress the death effectors and thereb...
International audienceTriple negative breast cancers (TNBC) without BRCA1/2 gene mutation or BRCAnes...
The proteins of the B-cell lymphoma 2 (Bcl-2) family are important regulators of apoptosis under nor...
The Bcl-2 family of proteins plays a critical role regulating apoptosis, and pro-survival Bcl-2 fami...
Members of the Bcl-2 family are proteins that play an essential role in the regulation of apoptosis,...
To become cancerous, a cell needs to overcome a num-ber of failsafe mechanisms [1]. It must evade ap...
The development of selective inhibitors for discrete anti-apoptotic BCL-2 family proteins implicated...
International audienceOne approach currently being developed in anticancer drug discovery is to sear...
International audienceBackground: Antiapoptotic Bcl-2 proteins are up-regulated in HTLV-1-infected T...
We report the isolation of bcl-x, a bcl-2-related gene that can function as a bcl-2-independent regu...
Members of the Bcl-2 family are proteins that play an essential role in the regulation of apoptosis,...
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
Interactions between the pro-survival and pro-apoptotic members of the Bcl-2 family of proteins dict...
Overexpression of two antiapoptotic proteins — Bcl-2 and Bcl-X L — is commonly observed in many canc...
Homoharringtonine (HHT) has been reported to be effective in a portion of patients with acute myeloi...
SummaryCancer cells hijack BCL-2 family survival proteins to suppress the death effectors and thereb...
International audienceTriple negative breast cancers (TNBC) without BRCA1/2 gene mutation or BRCAnes...
The proteins of the B-cell lymphoma 2 (Bcl-2) family are important regulators of apoptosis under nor...
The Bcl-2 family of proteins plays a critical role regulating apoptosis, and pro-survival Bcl-2 fami...
Members of the Bcl-2 family are proteins that play an essential role in the regulation of apoptosis,...
To become cancerous, a cell needs to overcome a num-ber of failsafe mechanisms [1]. It must evade ap...
The development of selective inhibitors for discrete anti-apoptotic BCL-2 family proteins implicated...
International audienceOne approach currently being developed in anticancer drug discovery is to sear...
International audienceBackground: Antiapoptotic Bcl-2 proteins are up-regulated in HTLV-1-infected T...
We report the isolation of bcl-x, a bcl-2-related gene that can function as a bcl-2-independent regu...
Members of the Bcl-2 family are proteins that play an essential role in the regulation of apoptosis,...
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
Interactions between the pro-survival and pro-apoptotic members of the Bcl-2 family of proteins dict...
Overexpression of two antiapoptotic proteins — Bcl-2 and Bcl-X L — is commonly observed in many canc...