Multiple Myeloma in Unusually Young

Multiple myeloma, a disease of elderly, is extremely rare in those about 30 years of age. A patient with MM diagnosed at age 27 is described. He was a male with a four-month history of back pain and later, hemurus and tibia pain persisting despite NSAIDS. X-rays had shown lytic lesions on lateral radiograph of the skull and the humerus. His ESR was 120 mm. Serum calcium was 125 mg/l and glomerular filtration rate at 25 ml/min. There was a beta2 peak in the serum protein electrophoresis. The Immunohistochemical examination demonstrated a strong reaction for the Lambda light chain in all tumor cells. Bence Jones protein was present in urine. Bone marrow bi-opsy confirmed the diagnosis of multiple myeloma. Our patient was treated with dexamethasone, zoledronic acid, cyclophosphamide and thalidomide with good evolution. Actually, he was pro-posed for stem cell transplantation. This report illustrated that multiple myeloma should be even evoked in young patients