Neurofibromatosis type 1 (NF1) is the most common monogenic disorder in which individuals manifest CNS abnormalities. Affected individuals develop glial neoplasms (optic gliomas, malignant astrocytomas) and neuronal dysfunction (learning disabilities, attention deficits). Nf1 genetically engineered mouse models have revealed the molecular and cellular underpinnings of gliomagenesis, attention deficit, and learning problems with relevance to basic neurobiology. Using NF1 as a model system, these studies have revealed critical roles for the NF1 gene in non-neoplastic cells in the tumor microenvironment, the importance of brain region heterogeneity, novel mechanisms of glial growth regulation, the neurochemical bases for attention deficit and ...
The neurofibromatoses (NF) encompass the rare diseases NF1, NF2, and schwannomatosis. The NFs affect...
The neurofibromatoses (NF) are autosomal dominant genetic disorders that encompass the rare diseases...
The neurofibromatoses (NF) are autosomal dominant genetic disorders that encompass the rare diseases...
Gliomas are the most common primary central nervous system tumors occurring in children and adults w...
Neurofibromatosis type 1 (NF1) is a common autosomal dominant neurologic condition characterized by ...
The 2011 annual meeting of the Children’s Tumor Foundation, the annual gathering of the neurofibroma...
The neurofibromatoses are inherited, tumor suppressor disorders that are characterized by multiple, ...
Neurofibromatosis Type 1 (NF1) is a genetic disease caused by mutations in Neurofibromin 1 (NF1). NF...
The neurofibromatoses (NF) encompass the rare diseases NF1, NF2, and schwannomatosis. The NFs affect...
As a cancer predisposition syndrome, individuals with neurofibromatosis type 1 (NF1) are at increase...
Neurofibromatosis Type I (NF1) is a common autosomal dominant disorder that afflicts approximately o...
The neurofibromatoses (NF) are autosomal dominant genetic disorders that encompass the rare diseases...
Organized and hosted by the Children's Tumor Foundation (CTF), the Neurofibromatosis (NF) conference...
The neurofibromatoses are inherited, tumor suppressor disorders that are characterized by multiple, ...
The neurofibromatoses represent two of the most common inherited tumor predisposition syndromes affe...
The neurofibromatoses (NF) encompass the rare diseases NF1, NF2, and schwannomatosis. The NFs affect...
The neurofibromatoses (NF) are autosomal dominant genetic disorders that encompass the rare diseases...
The neurofibromatoses (NF) are autosomal dominant genetic disorders that encompass the rare diseases...
Gliomas are the most common primary central nervous system tumors occurring in children and adults w...
Neurofibromatosis type 1 (NF1) is a common autosomal dominant neurologic condition characterized by ...
The 2011 annual meeting of the Children’s Tumor Foundation, the annual gathering of the neurofibroma...
The neurofibromatoses are inherited, tumor suppressor disorders that are characterized by multiple, ...
Neurofibromatosis Type 1 (NF1) is a genetic disease caused by mutations in Neurofibromin 1 (NF1). NF...
The neurofibromatoses (NF) encompass the rare diseases NF1, NF2, and schwannomatosis. The NFs affect...
As a cancer predisposition syndrome, individuals with neurofibromatosis type 1 (NF1) are at increase...
Neurofibromatosis Type I (NF1) is a common autosomal dominant disorder that afflicts approximately o...
The neurofibromatoses (NF) are autosomal dominant genetic disorders that encompass the rare diseases...
Organized and hosted by the Children's Tumor Foundation (CTF), the Neurofibromatosis (NF) conference...
The neurofibromatoses are inherited, tumor suppressor disorders that are characterized by multiple, ...
The neurofibromatoses represent two of the most common inherited tumor predisposition syndromes affe...
The neurofibromatoses (NF) encompass the rare diseases NF1, NF2, and schwannomatosis. The NFs affect...
The neurofibromatoses (NF) are autosomal dominant genetic disorders that encompass the rare diseases...
The neurofibromatoses (NF) are autosomal dominant genetic disorders that encompass the rare diseases...