Add to ORKGcidal activity of alveolar macrophages. Am. J. Physiol. 274 (Lung Cell. Mol. Physiol. 18): L270–L277, 1998.—Myco-plasma pneumoniae is a leading cause of pneumonia and exacerbates other respiratory diseases in humans. We inves-tigated the potential role of surfactant protein (SP) A in antimycoplasmal defense using alveolar macrophages (AMs) from C57BL/6NCr (C57BL) mice, which are highly resistant to infections of Mycoplasma pulmonis. C57BL AMs, activated with interferon (IFN)-g and incubated with SP-A (25 µg/ml) at 37°C, produced significant amounts of nitric oxide (zNO; nitrate and nitrite production 5 1.1 µM·h21 ·105 AMs21) and effected an 83 % decrease in mycoplasma colony-forming units (CFUs) by 6 h postinfection. Preincubation of AMs wi...
Abstract: Nitric oxide (NO) is important for combating bacterial infections in the lungs. Levels of ...
Immunosuppressed Swiss Black mice de®cient in surfactant protein A (SP-A2/2) and wild-type control m...
The role of alveolar macrophages (AM) in host defense against pulmonary infection has been difficult...
Alveolar macrophages (AM) are critical cell determinants of the pulmonary innate immune system and t...
apoptotic inflammatory cells by alveolar macrophages (AMs) is a key component of inflammation resolu...
Alveolar macrophages (AMs) are considered major effector cells in host defense against respiratory t...
Indirect evidence suggests that innate immune mechanisms involving alveolar macrophages (AMs) are of...
Surfactant protein-A (SP-A) has well-established functions in reducing bacterial and viral infection...
Background: M. pneumoniae and CARDS toxin interact with respiratory epithelium in the presence of su...
Recent studies strongly suggest that surfactant pro-tein D (SP-D) plays important roles in pulmonary...
Surfactant protein A (SP-A), a pulmonary member of the collectin family of proteins, facilitates the...
Mycoplasma pneumoniae (Mp), a common cause of pneumonia, is associated with asthma; however, the mec...
Lung surfactant protein A (SP-A) plays an important function in modulating inflammation in the lung....
Tumor necrosis factor-a (TNF-a) is a proinflammatory cytokine that appears to play a significant rol...
Surfactant protein (SP)-A and SP-D, members of the collectin family, are involved in innate host def...
Abstract: Nitric oxide (NO) is important for combating bacterial infections in the lungs. Levels of ...
Immunosuppressed Swiss Black mice de®cient in surfactant protein A (SP-A2/2) and wild-type control m...
The role of alveolar macrophages (AM) in host defense against pulmonary infection has been difficult...
Alveolar macrophages (AM) are critical cell determinants of the pulmonary innate immune system and t...
apoptotic inflammatory cells by alveolar macrophages (AMs) is a key component of inflammation resolu...
Alveolar macrophages (AMs) are considered major effector cells in host defense against respiratory t...
Indirect evidence suggests that innate immune mechanisms involving alveolar macrophages (AMs) are of...
Surfactant protein-A (SP-A) has well-established functions in reducing bacterial and viral infection...
Background: M. pneumoniae and CARDS toxin interact with respiratory epithelium in the presence of su...
Recent studies strongly suggest that surfactant pro-tein D (SP-D) plays important roles in pulmonary...
Surfactant protein A (SP-A), a pulmonary member of the collectin family of proteins, facilitates the...
Mycoplasma pneumoniae (Mp), a common cause of pneumonia, is associated with asthma; however, the mec...
Lung surfactant protein A (SP-A) plays an important function in modulating inflammation in the lung....
Tumor necrosis factor-a (TNF-a) is a proinflammatory cytokine that appears to play a significant rol...
Surfactant protein (SP)-A and SP-D, members of the collectin family, are involved in innate host def...
Abstract: Nitric oxide (NO) is important for combating bacterial infections in the lungs. Levels of ...
Immunosuppressed Swiss Black mice de®cient in surfactant protein A (SP-A2/2) and wild-type control m...
The role of alveolar macrophages (AM) in host defense against pulmonary infection has been difficult...
