Membranous nephropathy associated with gastrointestinal stromal tumour: a case report

Membranous nephropathy (MN) is a common cause of nephrotic syndrome in older adults. The association of MN with neoplasia has been controversial, but several recent studies have shown increase incidence of cancer in patients with MN [1]. We report a case of a 49-year-old male with severe nephrotic syndrome and concomitant jejunal gas-trointestinal stromal tumour (GIST). The combination of preoperative Imatinib mesylate chemotherapy and tumour excision was followed by complete resolution of protein-uria within 19 months, without specific treatment for MN. An association betweenMN andGIST has never previously been reported in the literature