1 1 Endophthalmitis following Open Globe Injury

Tel/fax number: 861068187998 Objective: To study the clinical characteristics of post-traumatic endophthalmitis following open-globe injury and identify factors affecting its frequency in order to gain further knowledge of possible risk factors for the development of endophthalmitis. Methods: We retrospectively reviewed all consecutive records of open globe injury cases (4968 eyes in 4865 inpatients) in 15 tertiary referral hospitals in China over 5 years (January 2001 to December 2005). The information was collected from a standardized database of eye injuries from which a detailed analysis of factors influencing the incidence of endophthalmitis was performed. Results: 173 eyes (1 bilateral rupture of a male) removed within 24 hours after trauma were excluded. We observed that 571 eyes (571 patients) out of a total of 4795 eyes (4693 patients) developed endophthalmitis and the rate of incidence was 11.91%. Laceration was an independent risk factor for open globe injury. Primary repair within 24 hrs, intraocular tissue prolapse and self-sealing of wounds seemed to impart protective effects against th