AND

In the use of ' ' Metheneamine " ( " Hexamethylenetetramine,'' "Urotropine") as a urinary antiseptic, some acid is customarily administered to maintain the acidity of the urine. Boric may be and is frequently used for this purpose. However, boric acid and borates are not without physiological effect when administered in sufficiently large amounts and if elimination does not proceed promptly, and accumulation takes place because of the slowness of elimination, toxic effects may result. Instances of harm arising from boric acid and borates are recorded in the liter-ature (1). Schattenfroh states (2): "Undoubtedly the use of boric acid and borates is fraught with danger. " Their use as preservatives in foods and food products is forbidden because of the belief that their presence in the foods that are consumed would be prejudicial to health. Voicu (3) has shown that the toxicity of boric acid to organ