Add to ORKGNovel insulin sensitizer modulates nutrient sensing pathways and maintains beta-cell phenotype in human islet
Background/Aims: Rodent islets are often used for basic science research but they do not always reca...
Receptors for insulin and insulin-like growth factor- I and insulin receptor substrate- I mediate pa...
Pancreatic ß-cells are often referred to as "fuel sensors" as they continually monitor and respond t...
Major bottlenecks in the expansion of human b-cell mass are limited proliferation, loss of b-cell ph...
Aims: To understand better the control of insulin secretion by human β cells and to identify similar...
Diabetes is a disease, characterized by the failure of the body to make or use insulin, resulting in...
Abstract: Insulin sensitivity and insulin secretion are reciprocally related such that insulin resis...
<p>(<b>A, B</b>) Human islets do not increase DNA synthesis in response to nutrients or insulin/IGF-...
Pancreatic β-cells are often referred to as “fuel sensors” as they continually monitor and respond t...
The Islets of Langerhans form a nutrient sensing network spread throughout the pancreas. They are ti...
Regulation of metabolic fuel homeostasis is a critical function of b-cells, which are located in the...
International audienceAIMS/HYPOTHESIS:Studies on beta cell metabolism are often conducted in rodent ...
AIMS/HYPOTHESIS: Ion fluxes constitute a major integrative signal in beta cells that leads to insuli...
Taken together the Islets of Langerhans form a nutrient sensing network spread throughout the pancre...
OBJECTIVE—Recent work has shown that insulin stimulates its own secretion in insulin-sensitive human...
Background/Aims: Rodent islets are often used for basic science research but they do not always reca...
Receptors for insulin and insulin-like growth factor- I and insulin receptor substrate- I mediate pa...
Pancreatic ß-cells are often referred to as "fuel sensors" as they continually monitor and respond t...
Major bottlenecks in the expansion of human b-cell mass are limited proliferation, loss of b-cell ph...
Aims: To understand better the control of insulin secretion by human β cells and to identify similar...
Diabetes is a disease, characterized by the failure of the body to make or use insulin, resulting in...
Abstract: Insulin sensitivity and insulin secretion are reciprocally related such that insulin resis...
<p>(<b>A, B</b>) Human islets do not increase DNA synthesis in response to nutrients or insulin/IGF-...
Pancreatic β-cells are often referred to as “fuel sensors” as they continually monitor and respond t...
The Islets of Langerhans form a nutrient sensing network spread throughout the pancreas. They are ti...
Regulation of metabolic fuel homeostasis is a critical function of b-cells, which are located in the...
International audienceAIMS/HYPOTHESIS:Studies on beta cell metabolism are often conducted in rodent ...
AIMS/HYPOTHESIS: Ion fluxes constitute a major integrative signal in beta cells that leads to insuli...
Taken together the Islets of Langerhans form a nutrient sensing network spread throughout the pancre...
OBJECTIVE—Recent work has shown that insulin stimulates its own secretion in insulin-sensitive human...
Background/Aims: Rodent islets are often used for basic science research but they do not always reca...
Receptors for insulin and insulin-like growth factor- I and insulin receptor substrate- I mediate pa...
Pancreatic ß-cells are often referred to as "fuel sensors" as they continually monitor and respond t...