Role of Temperature and Hyperglycemia

We planned a study to research the relations among blood pressure (BP), viscosity, and temperature in healthy sub-jects and among BP, viscosity, and glucose in diabetics. With simple random sampling method, 53 healthy and 29 diabetes mellitus (DM) type II subjects were selected. Parameters were determined with capillary viscometer and glucometer at 22°C, 36.5°C, and 39.5°C in healthy sub-jects, and at 22°C on diabetic patients during OGTT with 75 g of glucose. Statistical evaluations of the data were made with regression analysis, Student t test, Spearman’s correlation, and analysis of variance. When temperature decreased from 36.5°C to 22°C, blood viscosity increased 26.13%. This increase resulted in a 20.72 % decrease in blood flow rate. According to the Hagen-Poiseuille equa-tion, the required BP increase for compensation of the resulting tissue ischemia was 20.72%. Also, a 34.73% decrease in erythrocyte deformability and 18.71 % increase in plasma viscosity were seen. When temperature in-creased from 36.5 ° to 39.5°C, blood viscosity decreased 10.38%. This caused 11.15 % decrease in blood flow rate, and 11.15 % decrease in BP, according to the equation. Erythrocyte deformability increase of 9.92 % and plasma viscosity decrease of 4.99 % arose from the temperature rise. There is a correlation between total data for temper-atures and viscosities (r 5 20.84, P,.001). When the mean value of blood glucose increased from 100 to 400 mg/dL, viscosity increased 25 % (r 5 0.59, P 5.002). In this state, blood flow rate decrease was 20 % and BP increase for physiological compensation was 25%. Con-sequently, temperature, glucose and viscosity levels of blood are important factors for BP. Am J Hyperten