Virus-Induced Autophagy in Innate Immunity

Copyright: © 2014 Gu H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. When a virus invades a host cell, autophagy is triggered to maintain cellular homeostasis. Virus-induced autophagy is a double-edged sword in the antiviral function of host innate immunity. Unlike apoptosis, autophagy plays a different role in cell survival or inducing cell death. This mini-review summarizes recent developments in our understanding of the antiviral roles of autophagy in host innate immunity