Assessing the Burden of HPV-Associated Cancers in the United States Supplement to Cancer Toward Using National Cancer Surveillance Data for Preventing and Controlling Cervical and Other Human Papillomavirus-associated Cancers in the US

T his supplement, known as the ABHACUS (Assessing the Burdenof HPV-Associated Cancers in the United States) supplement, contains 22 articles. Together, these articles provide a comprehen-sive snapshot of data related to the occurrence and control of multi-ple cancers that have been associated with the human papillomavirus (HPV). These analyses highlight the burden of HPV-associated cancers in the US population as a whole and among vul-nerable population subgroups. We anticipate that these findings will be an important resource for enhancing existing strategies for the prevention and control of HPV-associated cancers. HPV is estimated to be responsible for 5.2 % of the cancers diag-nosed worldwide.1 Virtually 100 % of cervical cancers are causally associated with HPV, and there is increasing evidence of the role that HPV plays in other anogenital cancers and oropharyngeal can-cers. With the recent approval and recommendation of an HPV vac-cine that contains HPV–16 and HPV–18, interest in quantifying the Funded by the Centers for Disease Control an