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This study aims to understand the transport and dispersal of droplets produced by coughing in a ventilated room. Experiments were conducted to measure the initial velocity and the duration of a coughing burst. Computational fluid dynamics with a Eulerian–Lagrangian model was used to investigate the transport characteristics of evaporating droplets ex-pelled into the ventilated room. The simulation results indicate that if expelled horizontally the droplets finally settle if their initial size is 4100 mm, while if expelled upwards the droplets only settle if their initial size is 300 mm. Different ventilation set-ups vary in their ability to remove droplets produced by coughing. The mixing ventilation system has an almost equal effi