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Tassy, Oullier, Cermolacce, & Wicker1 inquire as to whether psychopathy was associated with differential activity in the dorsolateral prefrontal cortex (DLPFC) in our study of moral decision-making in psychopathy2. This is an important question that we had not considered previously. Tassy et al. also ask about behavioral responding and activity in another relevant brain region, the insula. Here we provide additional analyses of our data. We find that psychopathy is associated with increased activity in the dorsolateral prefrontal cortex during emotional moral decision-making. No significant relationship was observed between psychopathy and behavioral responses to the dilemmas. These findings, in conjunction with the reduced activity in emotion-related regions reported previously2, suggest that psychopathic individuals may use alternative strategies to make moral judgments; alternative interpretations are also discussed. Tassy et al. highlight the important role of the DLPFC in current theories regarding brain functioning in moral judgment. In particular, the DLPFC may play at least three distinctive roles: (1) to provide cognitive control to override prepotent social-emotional responses elicited by the dilemmas3, (2) to facilitate abstract reasoning (e.g. cost-benefit analyses),3,4 and (3) to generat