Genome Sequence of the Human-Pathogenetic Bacterium Vibrio vulnificus B2

Vibrio vulnificus, which can lead to rapidly expanding cellulitis or septicemia, is present in the marine environment. Here, we present the draft genome sequence of strain B2, which was isolated from a septicemia patient in 2010. Vibrio vulnificus is a human-opportunistic, Gram-negativepathogen, which is always present in marine environments and has been isolated from sediments, water, and many kinds of seafood, such as shrimp, fish, and oysters (2, 5, 12, 13). This bac-terium is highly lethal (50%) and has been reported to be the leading cause of seafood-borne death in the United States (3). It has also been widely isolated from Chinese seafood markets (14). Infection with this bacterium can lead to rapidly expanding cellu-litis or septicemia in predisposed individuals (5, 9). In this article, we sequenced and annotated the draft genomeof Vibrio vulnificus B2 isolated from a septicemia patient in 2010 in Zhejiang Province, China. The bacterial genomic DNA, isolated using the QIAamp DNAminikit (Qiagen, Germany), was paired-endwhole-genome shotgun sequencedusing IlluminaHiSeq 200