5 Медичні науки Scientific Journal «ScienceRise » №3/4(8)2015

вплив різних фармакотерапевтичних схем лікування на динамику показників запальної відповіді Ключові слова: хронічна хвороба нирок, гломерулонефрит, білки гострої фази запалення, гапто-глобін, церулоплазмін, α-2-макроглобулін In recent years the course processes of chronic glomerulonephritis viewed from a position of influence nonimmune factors. In the present research, in contrast to the existing, it is researched an intensity of acute phase response depending on the stage of chronic kidney disease and studied the dynamics of changes of inflammatory response against the background of different pharmacological regimens. Methods. Using standard biochemical tests to study the intensity of inflammatory response in chronic kid-ney disease of serum are studied protein content of acute phase: ceruloplasmin, haptoglobin, α-2-macroglobulin. The study involved 100 people. 80 of these people have chronic kidney disease. At hypertension was prescribed medicine of inhibitor of angiotensin-converting enzyme in combination with calcium channel blockers on a back-ground of basic therapy. Results. In all groups of patients before treatment it is recorded a high activity of serum of investigated proteins of acute phase, reflecting the presence of active inflammation. In the context of the treatment an inflam-mation activity is decreased, causing regression of the inflammatory response indicators. With the growth of th