Regulated endocytic trafficking of receptors is emerging as an important way to control receptor activity. Endocytosis of ligand-activated receptors can serve as a mechanism for either attenuating or enhancing signaling (Gonzalez-Gaitan, 2003; Miaczynska et al., 2004
Signaling by cell surface receptors appears to be relatively straight-forward: ligand binds to the e...
AbstractInternalization of receptors and other cell surface components is well known to occur via cl...
AbstractThe major process that regulates the amplitude and kinetics of signal transduction by tyrosi...
Regulated endocytic trafficking of receptors is emerging as an important way to control receptor act...
Cellular mechanisms of membrane traffic and signal transduction are deeply interconnected. The prese...
Endocytosis allows cells to transport particles and molecules across the plasma membrane. In additio...
<p>(a) The receptors (R) are activated by the binding of the ligand (RL = receptor ligand complex) a...
The intracellular trafficking machinery contributes to the spatial and temporal control of signaling...
Cellular responsiveness to many neuromodulators is controlled by endocytosis of the transmembrane re...
Cellular responsiveness to many neuromodulators is controlled by endocytosis of the transmembrane re...
Within any cellular signaling system membrane trafficking is a critical mechanism for cells to trans...
<p>Cellular responses to environmental signals are mediated by a host of signal transduction protein...
Endocytosis of cell surface receptors is involved in down-regulation of receptor activity. Recent fi...
receptors ed ylates the receptor: protein kinase A-mediated phos-Review TRENDS in Endocrinology and ...
Endocytosis is the major regulator of signaling from receptor tyrosine kinases (RTKs). The canonical...
Signaling by cell surface receptors appears to be relatively straight-forward: ligand binds to the e...
AbstractInternalization of receptors and other cell surface components is well known to occur via cl...
AbstractThe major process that regulates the amplitude and kinetics of signal transduction by tyrosi...
Regulated endocytic trafficking of receptors is emerging as an important way to control receptor act...
Cellular mechanisms of membrane traffic and signal transduction are deeply interconnected. The prese...
Endocytosis allows cells to transport particles and molecules across the plasma membrane. In additio...
<p>(a) The receptors (R) are activated by the binding of the ligand (RL = receptor ligand complex) a...
The intracellular trafficking machinery contributes to the spatial and temporal control of signaling...
Cellular responsiveness to many neuromodulators is controlled by endocytosis of the transmembrane re...
Cellular responsiveness to many neuromodulators is controlled by endocytosis of the transmembrane re...
Within any cellular signaling system membrane trafficking is a critical mechanism for cells to trans...
<p>Cellular responses to environmental signals are mediated by a host of signal transduction protein...
Endocytosis of cell surface receptors is involved in down-regulation of receptor activity. Recent fi...
receptors ed ylates the receptor: protein kinase A-mediated phos-Review TRENDS in Endocrinology and ...
Endocytosis is the major regulator of signaling from receptor tyrosine kinases (RTKs). The canonical...
Signaling by cell surface receptors appears to be relatively straight-forward: ligand binds to the e...
AbstractInternalization of receptors and other cell surface components is well known to occur via cl...
AbstractThe major process that regulates the amplitude and kinetics of signal transduction by tyrosi...