Brief Reports

Zidovudine has become the standard therapy for patients with altered immunity due to infection with human immu-nodeficiency virus (HIV). Initially, the drug was studied in patients who were in the advanced stages of HIV infection (1, 2). In that setting, it caused considerable but acceptable toxicity (1,2). More recently, zidovudine was shown to be effective in treating asymptomatic HIV-infected patients with low helper T-cell levels (3). As experience with the drug has grown, knowledge of the range of side effects has increased (1). We report the case of a patient with HIV infection and chronic anterior uveitis who had two episodes of serious visual impairment, which, in both instances, oc-curred shortly after the institution of zidovudine therapy. Case Report A 42-year-old man had had blurred vision in both eye