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Obstructive sleep apnea is prevalent in patients with pulmonary embolism Purpose: Obstructive sleep apnea (OSA) syndrome causes systemic consequences due to hypoxia and endothelial dysfunction. e purpose of this study was to investigate whether OSA is more common in subjects with pulmonary embolism (PE). Methods: is prospective study was conducted between November 2009 and December 2010 in the Department of Pulmonary Medicine of Gaziantep University. Twenty-eight patients with PE were included in the study group along with forty-ve subjects with OSA as the control group. e control group was selected from among subjects who were re-ferred to the sleep clinic. Full night polysomnography was performed for each subject. Results: Mean apnea-hypopnea index (AHI) was found to be higher in the PE group compared with the control group (p=0.010). Severe OSA was detected in 21.4 % of the PE group but in no controls (p=0.015). Sleep stage 2 was longer in control group whereas stage 1 and rapid eye movement (REM) sleep was longer in the PE group. Snoring and excessive daytime sleepiness were more common in the control group compared with the study group. AHI severity and thrombus localization were not signicantly dierent be-tween the groups (p=0.350). Conclusion: Our study ndings suggest that OSA is more prevalent and severe in subjects with PE compared with control subjects. e clinical signicance of less prevalent excessive daytime sleepiness and snoring in subjects with PE should be evaluated in further studies