Abstract: Dendritic cells (DCs) play an important role in bridging innate and adaptive immunity. These APCs have the ability to recognize specific molecular signatures of pathogens through TLRs. In particular, the intracellular TLR7 and TLR8, mediating the recognition of ssRNA by DCs, play a major role in the immune response during viral infection. Although differences have been identified between TLR7 and TLR8, in terms of cellular ex-pression and functions, the signaling pathways that lead to DC maturation following TLR7 or TLR8 en-gagement are largely unknown. We compared the signaling pathways involved in human CD34-DCmat-uration induced by agonists selective for TLR7 (imi-quimod) or TLR8 (3M002). TLR7 and TLR8 activa-tion up-regulated ...
Abstract Background Various microbial, inflammatory and immune signals regulate the activation of de...
Abstract Background Plasmacytoid Dendritic Cells (pDC) comprise approximately 0.2 to 0.8% of the blo...
EARLY ACTIVATION MARKERS EXPRESSED BY HUMAN PERIPHERAL DENDRITIC CELLS Peter Hellman and Håkan Er...
Although toll-like receptor (TLR) signals are critical for promoting antigen presenting cell maturat...
TLRs expressed on dendritic cells (DCs) differentially activate DCs when activated alone or in combi...
Toll-like receptors (TLR) recognize microbial and viral patterns and activate dendritic cells (DC). ...
TLRs interact with a growing list of pathogen-derived products and these interactions drive the acti...
Two major populations of dendritic cells (DCs), myeloid and plasmacytoid, can be isolated from human...
Dendritic cells (DC) are professional antigen-presenting cells of the immune system that play a key ...
Synthetic Toll-like receptor (TLR) 7 agonists have been suggested as immune modulators in a range of...
Novel approaches of dendritic cell (DC) based cancer immunotherapy aim at harnessing the unique attr...
SummaryToll-like receptors (TLRs) play prominent roles in initiating immune responses to infection, ...
International audienceOn recognition of influenza virus (Flu) by TLR7, plasmacytoid dendritic cells ...
BACKGROUND: Pathogen recognition by dendritic cells (DC) is crucial for the initiation of both innat...
BACKGROUND: Dendritic cells (DCs) determine the activation and polarization of T cells via expressio...
Abstract Background Various microbial, inflammatory and immune signals regulate the activation of de...
Abstract Background Plasmacytoid Dendritic Cells (pDC) comprise approximately 0.2 to 0.8% of the blo...
EARLY ACTIVATION MARKERS EXPRESSED BY HUMAN PERIPHERAL DENDRITIC CELLS Peter Hellman and Håkan Er...
Although toll-like receptor (TLR) signals are critical for promoting antigen presenting cell maturat...
TLRs expressed on dendritic cells (DCs) differentially activate DCs when activated alone or in combi...
Toll-like receptors (TLR) recognize microbial and viral patterns and activate dendritic cells (DC). ...
TLRs interact with a growing list of pathogen-derived products and these interactions drive the acti...
Two major populations of dendritic cells (DCs), myeloid and plasmacytoid, can be isolated from human...
Dendritic cells (DC) are professional antigen-presenting cells of the immune system that play a key ...
Synthetic Toll-like receptor (TLR) 7 agonists have been suggested as immune modulators in a range of...
Novel approaches of dendritic cell (DC) based cancer immunotherapy aim at harnessing the unique attr...
SummaryToll-like receptors (TLRs) play prominent roles in initiating immune responses to infection, ...
International audienceOn recognition of influenza virus (Flu) by TLR7, plasmacytoid dendritic cells ...
BACKGROUND: Pathogen recognition by dendritic cells (DC) is crucial for the initiation of both innat...
BACKGROUND: Dendritic cells (DCs) determine the activation and polarization of T cells via expressio...
Abstract Background Various microbial, inflammatory and immune signals regulate the activation of de...
Abstract Background Plasmacytoid Dendritic Cells (pDC) comprise approximately 0.2 to 0.8% of the blo...
EARLY ACTIVATION MARKERS EXPRESSED BY HUMAN PERIPHERAL DENDRITIC CELLS Peter Hellman and Håkan Er...