SUMMARY-Seven compounds, which are monomethyl derivatives of the previously tested 5'-(p-dimethylaminophenylazo)quinoline (05'), have now been prepared and tested for hepatocarcinogenic action in rats. The one omission is the 4'-methyl, which has not as yet been prepared. The com-pounds were tested in rats at the 0.03 % level and compared with p-dimethyl
To the livers of 150 rats, pellets of different size and shape prepared from cholesterol, anthracene...
Benzo[f]quinoline and benzo[h]quinoline are widespread environmental pollutants which have been foun...
ABSTRACT-Groups of 30 male Sprague-Dawley rats were given 4-nitrosomorpholine-3,3,5,5-d. in their dr...
were compared for rat hepatocarcinogenic activity at 0.03, 0.02, and 0.01 % levels in the diet. Two ...
ABSTRACT-The hepatocarcinogenic potencies of three newly identified hydroxymethyl derivatives of 4-(...
Ashby et al. (Carcinogenesis 1:1-7, 1980) have reported that 4-N-pyrrolidinylazobenzene is a power-f...
Active congeners of 6-methoxy-4-hydroxymethyl-3-methylquinoline, a lead compound with antineoplastic...
SINCE the suggestion was made that replicating liver cells may be especially sensitive to chemical c...
To estimate potential human risk of exposure to a food-derived, genotoxic hepatocarcinogen, 2-amino-...
To estimate potential human risk of exposure to a food-derived, genotoxic hepatocarcinogen, 2-amino-...
ABSTRACT-F344 ratl were treated with both unlabeled N-nltrolo-N-methylcyclohexylamlne (NMC) and deut...
The title compound is a strong carcinogen, similar in potency to benzo[a]pyrene in mouse skin assay....
'To whom correspondence should be addressed Quinoline is a hepatocarcinogen in rats and mice an...
As model compounds of a-hydroxy,/V-nitrosamines, four a-hydroperoxy W-nitrosamines were tested for t...
A major and previously undetected carcinogen-DNA adduct was found in the liv-ers of rats given N,N-d...
To the livers of 150 rats, pellets of different size and shape prepared from cholesterol, anthracene...
Benzo[f]quinoline and benzo[h]quinoline are widespread environmental pollutants which have been foun...
ABSTRACT-Groups of 30 male Sprague-Dawley rats were given 4-nitrosomorpholine-3,3,5,5-d. in their dr...
were compared for rat hepatocarcinogenic activity at 0.03, 0.02, and 0.01 % levels in the diet. Two ...
ABSTRACT-The hepatocarcinogenic potencies of three newly identified hydroxymethyl derivatives of 4-(...
Ashby et al. (Carcinogenesis 1:1-7, 1980) have reported that 4-N-pyrrolidinylazobenzene is a power-f...
Active congeners of 6-methoxy-4-hydroxymethyl-3-methylquinoline, a lead compound with antineoplastic...
SINCE the suggestion was made that replicating liver cells may be especially sensitive to chemical c...
To estimate potential human risk of exposure to a food-derived, genotoxic hepatocarcinogen, 2-amino-...
To estimate potential human risk of exposure to a food-derived, genotoxic hepatocarcinogen, 2-amino-...
ABSTRACT-F344 ratl were treated with both unlabeled N-nltrolo-N-methylcyclohexylamlne (NMC) and deut...
The title compound is a strong carcinogen, similar in potency to benzo[a]pyrene in mouse skin assay....
'To whom correspondence should be addressed Quinoline is a hepatocarcinogen in rats and mice an...
As model compounds of a-hydroxy,/V-nitrosamines, four a-hydroperoxy W-nitrosamines were tested for t...
A major and previously undetected carcinogen-DNA adduct was found in the liv-ers of rats given N,N-d...
To the livers of 150 rats, pellets of different size and shape prepared from cholesterol, anthracene...
Benzo[f]quinoline and benzo[h]quinoline are widespread environmental pollutants which have been foun...
ABSTRACT-Groups of 30 male Sprague-Dawley rats were given 4-nitrosomorpholine-3,3,5,5-d. in their dr...