Resistance Testing in Drug-Naive HIV-Infected Patients: Is it Time?

Early recommendations for the use of an-tiretroviral drug resistance testing in 1998 cautiously endorsed its use for persons who have experienced treatment failure, with a possible role for persons identified with recent HIV infection [1]. More recent recommendations now include clear rec-ommendations for resistance testing in persons with treatment failure and in those with HIV infection of!2 years ’ du-ration, and suggest considering resistance testing for drug-naive patients in areas with a prevalence of resistance of 5% [2]. In this issue of the journal, Sax et al. [3] present a cost-effectiveness analysi