Anti-wrinkle Effect of Facial Mask Pack Containing Oinon (Allium cepa) Skin Extracts

Abstract: In this study, the domestic onion skin has been used to investigate the anti-wrinkle effect of the ethanolic extract. The onion skin has been known to contain a large amount of antioxidant including quercetin. Solvent extraction by 80 % ethanol was carried out of the onion skin. The high amount of quercetin have been identified using HPLC as a bioactive compound. The extraction yield of the quercetin increased according to temperature up to 80oC. Two different antioxidant assays (DPPH and ABTS) were performed to determine the free-radical scavenging activity of onion skin extracts. The antioxidant activities (EC50 of DPPH) of the vitamin C and the onion extracts were 2.2 and 5.09 µg/mL, respectively. The results of ABTS tests were 2.33 (of vitamin C) and 2.40 µg/mL (of the onion extracts), respectively. In a clinical study, a panel of 10 female volunteers between th