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The pharmaceutical industry is currently shifting from batch to continuous manufacturing, and for downstream processes, this shift can reduce costs and improve quality provided the new unit operations are chosen properly. Electrospinning, a method of making nanofiber mats from solutions of an active pharmaceutical ingredient (API), polymer and solvent, has shown great promise for producing final solid dosage forms with minimal process steps. In this thesis, we explore the use of electrospinning to produce fiber mats containing either amorphous or crystalline API, aiming to develop the process such that it can be used for a wide variety of final drug products. Key to utilizing electrospinning to make these products is understanding the composition and behavior of the final fiber mats. For fibers containing amorphous API, this means it is essential to understand the level of mixing between API and polymer and the stability of the final product, and for fibers containing crystalline API, the crystal morphology and extent of dispersion within the polymer must be understood. The mixing level of amorphous API and polymer in fibers was analyzed using solid state nuclear magnetic resonance relaxation times. It was found that, for aliskiren/poly(viny