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ings. Further diagnostic tests are then ordered using a hypothesis-driven approach to add laboratory evidence in support of or against the clinical suspicion. Electrodiag-nostic (EDX) studies, in this respect, are an extension of the physical examination and may help establish the diagnosis of myopathy. EDX studies, however, are not always needed to diagnose a myopathy. This is particularly true in the pediatric and, occasionally, the adult population. Oftentimes, patients with inherited myopathies present with characteristic phenotypes, and, possibly, a positive family history. In these cases, it is reasonable to proceed directly to genetic testing. In addition, at times, the diagnosis ultimately requires a muscle biopsy, regardless of the EDX study results. Therefore, if clinical suspicion for a myop-athy is high, generally corroborated by elevated creatine kinase (CK) levels, it is often ilitation Hospital