Commentary

On the cause of serous detachments and acute central serous chorioretinopathy Serous detachments, with bullous elevation of the retina, occur in a variety of disorders including central serous chorioretinopathy (CSC), age related macular degenera-tion, lupus erythematosus, choroidal ischaemic disorders such as accelerated hypertension and pre-eclampsia, systemic corticosteroid usage, over some choroidal tu-mours, and in inflammatory disorders such as Harada’s disease. There is little mystery about the appearance of fluid when it overlies a large area of leaky retinal pigment epithelium (RPE), which itself overlies exudative choroidal inflammation or vasculopathy. However, the development and persistence of elevated detachment is rather curious in disorders such as CSC where the region of leakage is ver