RESEARCH ARTICLE Incidence, Characteristics and Risk Factors of Acute Kidney Injury among Dengue Patients: A Retrospective Analysis

Background Dengue induced acute kidney injury (AKI) imposes heavy burden of illness in terms of mor-bidity and mortality. A retrospective study was conducted to investigate incidence, charac-teristics, risk factors and clinical outcomes of AKI among dengue patients. Methodology A total 667 dengue patients (2008–2013) were retrospectively evaluated and were stratified into AKI and non-AKI groups by using AKIN criteria. Two groups were compared by using appropriate statistical methods. Results There were 95 patients (14.2%) who had AKI, with AKIN-I, AKIN-II and AKIN-III in 76.8%, 16.8 % and 6.4 % patients, respectively. Significant differences (P<0.05) in demographics and clinico-laboratory characteristics were observed between patients with and without AKI. Presence of dengue hemorrhagic fever [OR (95 % CI): 8.0 (3.64–17.59), P<0.001], rhabdomyolysis [OR (95 % CI): 7.9 (3.04–20.49)], multiple organ dysfunction [OR (95 % CI)