Solvent Effect on the Nature of the Metallamacrocycles Formed:

Depending on the choice of coordinating solvent molecules, the size and nuclearity of metallamacrocycles formed could be controlled. When a manganese ion was assembled with a pentadentate ligand, N-trans-(pentenoyl)salicylhydrazide in amide solvents such as dimethylformamide (DMF) or dimethylacetamide (DMA), an S 6 symmetry puckered dodecanuclear metalladiazamacrocycle with a ···(ΛΛΔΔ)(ΛΛΔΔ)·· · chiral sequence was obtained. However, in an alcoholic solvent such as methanol or ethanol while keeping the other conditions the same, an S 8 symmetry octanuclear metalladiazamacrocycle with a ···(ΛΔ)(ΛΔ)·· · chiral sequence was obtained