Add to ORKGSummary: We present a program to improve haplotype recon-struction by incorporating information from paired-end reads, and demonstrate its utility on simulated data. We find that given a fixed coverage, longer reads (implying fewer of them) are preferable. Availability: The executable and user manual can be freely downloaded fro
When we sequence a diploid individual, the output actually comprises two genomes: one from the pater...
Background Expansions of short tandem repeats are the cause of many neurogenetic di...
Abstract Background Pooling techniques, where multiple sub-samples are mixed in a single sample, are...
Summary: We present a program to improve haplotype reconstruction by incorporating information from ...
Haplotypic sequences contain significantly more information than genotypes of genetic markers and ar...
The human genome is diploid, that is each of its chromosomes comes in two copies. This requires to p...
High-throughput sequencing technologies produce short sequence reads that can contain phase informat...
Motivation: Haplotype assembly is the computational problem of reconstructing haplotypes in diploid ...
The human genome is diploid, which requires assigning heterozygous single nucleotide polymorphisms (...
Abstract Background Haplotype assembly is the process of assigning the different alleles of the vari...
Despite their accuracy, next-generation DNA sequencing technologies have limited utility in analyzin...
High-throughput sequencing technologies produce short sequence reads that can contain phase informat...
Motivation: Haplotype assembly is the computational problem of reconstructing haplotypes in diploid ...
The human genome is diploid, which requires assigning heterozygous single nucleotide polymorphisms (...
Background: Haplotype information is essential for many genetic and genomic analyses, including geno...
When we sequence a diploid individual, the output actually comprises two genomes: one from the pater...
Background Expansions of short tandem repeats are the cause of many neurogenetic di...
Abstract Background Pooling techniques, where multiple sub-samples are mixed in a single sample, are...
Summary: We present a program to improve haplotype reconstruction by incorporating information from ...
Haplotypic sequences contain significantly more information than genotypes of genetic markers and ar...
The human genome is diploid, that is each of its chromosomes comes in two copies. This requires to p...
High-throughput sequencing technologies produce short sequence reads that can contain phase informat...
Motivation: Haplotype assembly is the computational problem of reconstructing haplotypes in diploid ...
The human genome is diploid, which requires assigning heterozygous single nucleotide polymorphisms (...
Abstract Background Haplotype assembly is the process of assigning the different alleles of the vari...
Despite their accuracy, next-generation DNA sequencing technologies have limited utility in analyzin...
High-throughput sequencing technologies produce short sequence reads that can contain phase informat...
Motivation: Haplotype assembly is the computational problem of reconstructing haplotypes in diploid ...
The human genome is diploid, which requires assigning heterozygous single nucleotide polymorphisms (...
Background: Haplotype information is essential for many genetic and genomic analyses, including geno...
When we sequence a diploid individual, the output actually comprises two genomes: one from the pater...
Background Expansions of short tandem repeats are the cause of many neurogenetic di...
Abstract Background Pooling techniques, where multiple sub-samples are mixed in a single sample, are...