Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Nephritis represents a frequent, severe complication of systemic lupus erythematosus. Autoantibodies appear to be fundamental in the pathogenesis of lupus nephritis. Several hypotheses are currently experimentally tested to further elucidate the direct induction of inflammation through interaction of the pathological autoantibodies with intrinsic glomerular components and the triggering of a complement-driven autoinflammatory cascade. B-cells have, in the last decade, emerged as a promising new therapeutic target, as biological treatments successfully attempting B-cell depletion, inhibition of B-ce...
B cells are critical players in the orchestration of properly regulated immune responses, nor-mally ...
Copyright © 2014 Jin-Shuen Chen et al.This is an open access article distributed under the Creative ...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of ...
Nephritis represents a frequent, severe complication of systemic lupus erythematosus. Autoantibodies...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
Loss of B-cell tolerance is a hallmark feature of the pathogenesis in systemic lupus erythematosus (...
Systemic lupus erythematosus (SLE) is a complex disease characterizedby numerous autoantibodies and ...
Copyright © 2012 Christiane S. Hampe.is is an open access article distributed under theCreativeCommo...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
Lupus\ua0Nephritis (LN) is a severe manifestation of Systemic Lupus Erythematosus (SLE) with a signi...
Copyright © 2013 Gabriel J. Tobón et al.This is an open access article distributed under theCreativ...
PURPOSE OF REVIEW:The management of lupus nephritis remains unsatisfactory due to insufficiently eff...
PURPOSE OF REVIEW:The management of lupus nephritis remains unsatisfactory due to insufficiently eff...
PURPOSE OF REVIEW:The management of lupus nephritis remains unsatisfactory due to insufficiently eff...
Lupus nephritis (LN) in systemic lupus erythematosus (SLE) remains a major cause of morbidity and en...
B cells are critical players in the orchestration of properly regulated immune responses, nor-mally ...
Copyright © 2014 Jin-Shuen Chen et al.This is an open access article distributed under the Creative ...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of ...
Nephritis represents a frequent, severe complication of systemic lupus erythematosus. Autoantibodies...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
Loss of B-cell tolerance is a hallmark feature of the pathogenesis in systemic lupus erythematosus (...
Systemic lupus erythematosus (SLE) is a complex disease characterizedby numerous autoantibodies and ...
Copyright © 2012 Christiane S. Hampe.is is an open access article distributed under theCreativeCommo...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
Lupus\ua0Nephritis (LN) is a severe manifestation of Systemic Lupus Erythematosus (SLE) with a signi...
Copyright © 2013 Gabriel J. Tobón et al.This is an open access article distributed under theCreativ...
PURPOSE OF REVIEW:The management of lupus nephritis remains unsatisfactory due to insufficiently eff...
PURPOSE OF REVIEW:The management of lupus nephritis remains unsatisfactory due to insufficiently eff...
PURPOSE OF REVIEW:The management of lupus nephritis remains unsatisfactory due to insufficiently eff...
Lupus nephritis (LN) in systemic lupus erythematosus (SLE) remains a major cause of morbidity and en...
B cells are critical players in the orchestration of properly regulated immune responses, nor-mally ...
Copyright © 2014 Jin-Shuen Chen et al.This is an open access article distributed under the Creative ...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of ...