DOI: 10.13189/ujph.2015.030203 Risk Factors for Multi-drug Resistant Tuberculosis in Addis Ababa, Ethiopia

is becoming a major challenge of the tuberculosis (TB) control program in Ethiopia. The objective of the study was to investigate risk factors for MDR-TB in Addis Ababa. Comparative cross-sectional study was conducted to determine the risk factors for MDR-TB in Addis Ababa. MDR and non MDR-TB cases were compared on key socio-demographic and patient related clinical features for multidrug-resistance. A total 439 (113 MDR-TB and 326 non MDR-TB) were enrolled in to the study. Standard data abstraction instrument were used. Data were entered and analysed using SPSS version 18 for windows. Initial descriptive analyses of all variables of interest, odds ratio, univariate and subsequent multiple regression analysis was carried out. Male sex (OR 2, 95%CI 1.4-5), younger age of 15-34 years (OR 2.8, 95%CI 1.7–6.4), twice or more episodes of TB treatment (OR 14, 95%CI 1.3-9), treatmen