Decreasing incidence of herpes zoster in the highly active antiretroviral therapy era. Clin Infect Dis 2013; 57:122–5

We evaluated the effect of highly active antiretroviral ther-apy (HAART) on the incidence of herpes zoster (HZ) in human immunodeficiency virus (HIV)–infected subjects. The annual incidence of HZ per 100 person-years decreased significantly from 6.3 episodes in 1987 to 1.0 episode in 2011, probably reflecting improved immune function