Background. Adolescents represent the fastest growing demographic group of new human immunodeficiency virus (HIV) infections in the United States. At present, there is little information available about their response to therapy. Methods. We studied 120 adolescents infected via high-risk behaviors who began receiving highly active antiretroviral therapy (HAART), to determine their virologic and immunologic response to therapy. Results. Subjects were enrolled at 28 sites of the Pediatric Acquired Immunodeficiency Syndrome Clinical Trials Group. After 16–24 weeks of HAART, 59 % of subjects had reproducible undetectable virus loads, according to repeat measurements (virologic success). As enumerated by flow-cytometric analysis, increases in le...
HIV-infected children in resource-limited settings are increasingly gaining greater access to highly...
BACKGROUND: Measures of immune outcomes in youth who initiate combination antiretroviral therapy (cA...
Children differ from adults in both natural history of HIV-1 infection and their response to antiret...
Background. Adolescents represent the fastest growing demographic group of new human immunodeficienc...
Every year, HIV-positive adolescents add to the growing number of HIV-infected individuals. In fact,...
Every year, HIV-positive adolescents add to the growing number of HIV-infected individuals. In fact,...
We studied changes in 60 immunological parameters after the administration of highly active antiretr...
Abstract: Immune repopulation, despite virological failure, often occurs in children under highly ac...
BackgroundEarly treatment studies have shown that prompt treatment of HIV with combination antiretro...
Background: HIV-1-infected children show changes of blood lymphocyte subpopulations. We have, theref...
Current antiretroviral therapy (ART) guidelines recommend treating all children with HIV-1 infection...
Treatment failure and drug resistance create obstacles to long-term management of HIV-1 infection. N...
Background: The capacity of the immune system of adolescents to generate and repopulate naive and me...
This study examined the rate of decline in plasma human immunode®ciency virus type 1 (HIV-1) RNA lev...
Objective Medication adherence is often suboptimal for adolescents with HIV, and establishing corre...
HIV-infected children in resource-limited settings are increasingly gaining greater access to highly...
BACKGROUND: Measures of immune outcomes in youth who initiate combination antiretroviral therapy (cA...
Children differ from adults in both natural history of HIV-1 infection and their response to antiret...
Background. Adolescents represent the fastest growing demographic group of new human immunodeficienc...
Every year, HIV-positive adolescents add to the growing number of HIV-infected individuals. In fact,...
Every year, HIV-positive adolescents add to the growing number of HIV-infected individuals. In fact,...
We studied changes in 60 immunological parameters after the administration of highly active antiretr...
Abstract: Immune repopulation, despite virological failure, often occurs in children under highly ac...
BackgroundEarly treatment studies have shown that prompt treatment of HIV with combination antiretro...
Background: HIV-1-infected children show changes of blood lymphocyte subpopulations. We have, theref...
Current antiretroviral therapy (ART) guidelines recommend treating all children with HIV-1 infection...
Treatment failure and drug resistance create obstacles to long-term management of HIV-1 infection. N...
Background: The capacity of the immune system of adolescents to generate and repopulate naive and me...
This study examined the rate of decline in plasma human immunode®ciency virus type 1 (HIV-1) RNA lev...
Objective Medication adherence is often suboptimal for adolescents with HIV, and establishing corre...
HIV-infected children in resource-limited settings are increasingly gaining greater access to highly...
BACKGROUND: Measures of immune outcomes in youth who initiate combination antiretroviral therapy (cA...
Children differ from adults in both natural history of HIV-1 infection and their response to antiret...