Patients needing long-term platelet transfusion support become alloimmunized to transplantation (HL-A) antigens present in random-donor blood products, which results in refractoriness to platelets from unselected donors. Three thousand HL-A typed donors were used to evaluate the effectiveness of selecting unrelated platelet donors for alloimmunized patients by donor-recipient lymphocyte HL-A compatibility. Platelet transfusions from HL-A compatible donors resulted in increased platelet increments after transfusion. There was a positive correlation between the degree of donor-recipient HL-A compatibility and the transfusion response; the responses to platelets from A-matched donors (HL-A identical) and B-1-matched donors (HL-A compatible, on...
man platelet transfusions, nine thrombocytopenic pa-tients with bone marrow failure were given 6 U (...
The presence of anti-HL-A antibodies in a polytransfused person very often is a sign of a bad progno...
BACKGROUND: For HLA-alloimmunized patients, platelet (PLT) concentrations are provided either at mat...
Patients receiving repeated transfusions sooner or later develop an anti-HL-A immunization. To preve...
Background: The selection of compatible human leukocyte antigen platelets has been associated with i...
AbstractBackgroundSuccessful transfusion of platelet refractory patients is a challenge. Many potent...
Platelet transfusion refractoriness (PTR) is the major complication of long-term platelet supportive...
Patients refractory to platelet transfusions because of alloimmunization require HLA-matched platele...
BACKGROUND Recipients of platelet transfusions with 1-hour corrected count increments (1hCCIs) of 7....
Platelet transfusion refractoriness results in adverse outcomes and increased health care costs. Man...
Transfusion plays an important role in the management of patients with hematological malignancies a...
Despite the use of HIA-matched platelets for alloimmu-nized recipients. transfusion failures occur. ...
The effect of variation in platelet function in platelet donors on patient outcome following platele...
Item does not contain fulltextPlatelet transfusions are indispensable for supportive care of patient...
The effectiveness of platelet transfusions, an essential supportive care for mostly hemato-oncologic...
man platelet transfusions, nine thrombocytopenic pa-tients with bone marrow failure were given 6 U (...
The presence of anti-HL-A antibodies in a polytransfused person very often is a sign of a bad progno...
BACKGROUND: For HLA-alloimmunized patients, platelet (PLT) concentrations are provided either at mat...
Patients receiving repeated transfusions sooner or later develop an anti-HL-A immunization. To preve...
Background: The selection of compatible human leukocyte antigen platelets has been associated with i...
AbstractBackgroundSuccessful transfusion of platelet refractory patients is a challenge. Many potent...
Platelet transfusion refractoriness (PTR) is the major complication of long-term platelet supportive...
Patients refractory to platelet transfusions because of alloimmunization require HLA-matched platele...
BACKGROUND Recipients of platelet transfusions with 1-hour corrected count increments (1hCCIs) of 7....
Platelet transfusion refractoriness results in adverse outcomes and increased health care costs. Man...
Transfusion plays an important role in the management of patients with hematological malignancies a...
Despite the use of HIA-matched platelets for alloimmu-nized recipients. transfusion failures occur. ...
The effect of variation in platelet function in platelet donors on patient outcome following platele...
Item does not contain fulltextPlatelet transfusions are indispensable for supportive care of patient...
The effectiveness of platelet transfusions, an essential supportive care for mostly hemato-oncologic...
man platelet transfusions, nine thrombocytopenic pa-tients with bone marrow failure were given 6 U (...
The presence of anti-HL-A antibodies in a polytransfused person very often is a sign of a bad progno...
BACKGROUND: For HLA-alloimmunized patients, platelet (PLT) concentrations are provided either at mat...