Add to ORKGMotivation: RNA sequence design is studied at least as long as the classical folding problem. While for the latter the functional fold of an RNA molecule is to be found, inverse folding tries to identify RNA sequences that fold into a function-specific target structure. In combination with RNA-based biotechnology and synthetic biology, reliable RNA sequence design becomes a crucial step to generate novel biochemical components. Results: In this article, the computational tool antaRNA is presented. It is capable of compiling RNA sequences for a given structure that comply in addition with an adjustable full range objective GC-content distribution, specific sequence constraints and additional fuzzy structure constraints. antaRNA applies ant c...
Synthetic biology and nanotechnology are poised to make revolutionary contributions to the 21st cent...
Motivation: The structure of RNA molecules is often crucial for their function. Therefore, secondary...
International audienceThe development of algorithms for designing artificial RNA sequences that fold...
Motivation: RNA sequence design is studied at least as long as the classical folding problem. Althou...
International audienceComputational programs for predicting RNA sequences with desired folding prope...
The structure of RNA molecules is often crucial for their function. Therefore, designing RNA sequenc...
RNA has become an integral building material in synthetic biology. Dominated by their secondary stru...
Rubio-Largo, A., Vanneschi, L., Castelli, M., & Vega-Rodriguez, M. A. (2019). Multiobjective Metaheu...
International audienceThe overall architecture of an RNA can be predicted with acceptable accuracy u...
Ribonucleic Acids (RNAs) are extremely important biomolecules that are involved in many cellular pro...
International audienceIn recent years, new methods for computational RNA design have been developed ...
Background RNA secondary structure prediction, or folding, is a classic problem in bioinformatics: ...
RNA molecules, the fundamental building blocks of life, are chains of nucleotides that can bond to p...
International audienceThe problem of RNA secondary structure design (also called inverse folding) is...
Synthetic biology and nanotechnology are poised to make revolutionary contributions to the 21st cent...
Motivation: The structure of RNA molecules is often crucial for their function. Therefore, secondary...
International audienceThe development of algorithms for designing artificial RNA sequences that fold...
Motivation: RNA sequence design is studied at least as long as the classical folding problem. Althou...
International audienceComputational programs for predicting RNA sequences with desired folding prope...
The structure of RNA molecules is often crucial for their function. Therefore, designing RNA sequenc...
RNA has become an integral building material in synthetic biology. Dominated by their secondary stru...
Rubio-Largo, A., Vanneschi, L., Castelli, M., & Vega-Rodriguez, M. A. (2019). Multiobjective Metaheu...
International audienceThe overall architecture of an RNA can be predicted with acceptable accuracy u...
Ribonucleic Acids (RNAs) are extremely important biomolecules that are involved in many cellular pro...
International audienceIn recent years, new methods for computational RNA design have been developed ...
Background RNA secondary structure prediction, or folding, is a classic problem in bioinformatics: ...
RNA molecules, the fundamental building blocks of life, are chains of nucleotides that can bond to p...
International audienceThe problem of RNA secondary structure design (also called inverse folding) is...
Synthetic biology and nanotechnology are poised to make revolutionary contributions to the 21st cent...
Motivation: The structure of RNA molecules is often crucial for their function. Therefore, secondary...
International audienceThe development of algorithms for designing artificial RNA sequences that fold...