Mcl-1 is a member of the Bcl-2 family that was identified calcium ionophore, or UV irradiation) and the withdrawal of based on increased expression in myeloblastic leukemia required growth factors. In addition, Mcl-1 was found to cells undergoing differentiation. Mcl-1 was previously found interact with Bax, a member of the Bcl-2 family that pro-to be similar to Bcl-2 in causing a delay in apoptotic cell motes cell death as a homodimer but that can heterodimer-death in Chinese hamster ovary cells. The work described ize with Bcl-2 to promote cell viability. Although Mcl-1 pro-here was aimed at determining whether Mcl-1 could also longed cell viability, it did not prevent eventual cell death exert such an effect in hematopoietic cells, becau...
Evasion of apoptosis is critical for tumorigenesis, and sustained survival of nascent neoplastic cel...
Programmed apoptotic cell death is critical to maintain tissue homeostasis and cellular integrity in...
The Bcl-2 family, which plays important roles in controlling cancer development, is divided into ant...
MCL-1 (myeloid cell leukemia-1), a member of the BCL-2 family, has three splicing variants, antiapop...
The anti-apoptotic proteins Mcl-1 and Bcl-2 have been shown to be critical in T cell development and...
<div><p>MCL-1 (myeloid cell leukemia-1), a member of the BCL-2 family, has three splicing variants, ...
© 2015 Dr. Natasha Sarah AnsteeCell death by apoptosis plays a critical role during embryonic develo...
Pro-survival BCL-2 family members protect cells from programmed cell death that can be induced by mu...
Pro-survival BCL-2 family members protect cells from programmed cell death that can be induced by mu...
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
Pro-survival BCL-2 family members protect cells from programmed cell death that can be induced by mu...
Acute myeloid leukemia (AML) frequently relapses after initial treatment. Drug resistance in AML has...
AbstractThe maintenance of homeostasis in normal tissues reflects a balance between cell proliferati...
Myeloid cell leukemia-1 (Mcl-1) is an antiapoptotic member of the Bcl-2 protein family. It interacts...
Mcl-1 is an anti-apoptotic member of the Bcl-2 family of proteins. Enforced expression of Mcl-1 pro...
Evasion of apoptosis is critical for tumorigenesis, and sustained survival of nascent neoplastic cel...
Programmed apoptotic cell death is critical to maintain tissue homeostasis and cellular integrity in...
The Bcl-2 family, which plays important roles in controlling cancer development, is divided into ant...
MCL-1 (myeloid cell leukemia-1), a member of the BCL-2 family, has three splicing variants, antiapop...
The anti-apoptotic proteins Mcl-1 and Bcl-2 have been shown to be critical in T cell development and...
<div><p>MCL-1 (myeloid cell leukemia-1), a member of the BCL-2 family, has three splicing variants, ...
© 2015 Dr. Natasha Sarah AnsteeCell death by apoptosis plays a critical role during embryonic develo...
Pro-survival BCL-2 family members protect cells from programmed cell death that can be induced by mu...
Pro-survival BCL-2 family members protect cells from programmed cell death that can be induced by mu...
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
Pro-survival BCL-2 family members protect cells from programmed cell death that can be induced by mu...
Acute myeloid leukemia (AML) frequently relapses after initial treatment. Drug resistance in AML has...
AbstractThe maintenance of homeostasis in normal tissues reflects a balance between cell proliferati...
Myeloid cell leukemia-1 (Mcl-1) is an antiapoptotic member of the Bcl-2 protein family. It interacts...
Mcl-1 is an anti-apoptotic member of the Bcl-2 family of proteins. Enforced expression of Mcl-1 pro...
Evasion of apoptosis is critical for tumorigenesis, and sustained survival of nascent neoplastic cel...
Programmed apoptotic cell death is critical to maintain tissue homeostasis and cellular integrity in...
The Bcl-2 family, which plays important roles in controlling cancer development, is divided into ant...