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)Conclusions: There is evidence that topical metronidazole and azelaic acid are effective. There is some evidence that oral metronidazole and tetracycline are effective. More well-designed, randomized controlled trials are required to provide better evidence of the efficacy and safety of other rosacea therapies. ( J Am Acad Dermatol 2007;56:107-15.) R osacea is a chronic condition characterized by recurrent episodes of facial flushing, ery-thema, papules, pustules, and telangiectasia in a symmetrical, facial distribution.1-4 Several well-defined types of rosacea are described including erythematotelangiectatic rosacea, papulopustular rosacea, phymatous rosacea, ocular rosacea, and the variant granulomatous rosacea.3,4 Ocular rosacea can develop without involvement of other areas of the skin and may wax and wane.2,5 Rosacea usuall