Elevated expression of syntenin in breast cancer is correlated with lymph node metastasis and poor patient survival Yu Yang1,2, Qi Hong1,2, Pengcheng Shi1, Zhebin Liu1, Jianmin Luo1 and Zhiming Shao1,2* Introduction: Syntenin is a scaffolding-PDZ domain-containing protein. Although it is reported that syntenin is associated with melanoma growth and metastasis, the possible role of syntenin in breast cancer has not been well elucidated. The present study investigated the expression and function of syntenin in breast cancer. Methods: Real-time polymerase chain reaction (PCR) and Western blots were used to determine the mRNA and protein expression of syntenin. With a combination of overexpression and RNA interference, the effect of synteni
The ability of cancer cells to invade underlies metastatic progression. One mechanism by which cance...
Current evidences suggest that expression of Ki67, cyclooxygenase (COX), aromatase, adipokines, pros...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
The scaffold protein syntenin abounds during fetal life where it is important for developmental move...
Multiple studies indicate that the gain-of-function of syntenin-1 (hereupon referred to as ‘syntenin...
Melanoma differentiation associated gene-9 (MDA-9), Syntenin-1, or syndecan binding protein is a dif...
Metastasis represents a key factor associated with poor prognosis of head and neck squamous cell car...
Erjie Xia,* Xiaofen Zhou,* Adheesh Bhandari, Xiaohua Zhang, Ouchen Wang Department of Thyroid & ...
Cancer exosomes are gaining considerable amount of attention in basic and applied clinical research ...
Background. The extraordinary invasiveness of human glioblastoma multiforme (GBM) contributes to tre...
International audienceThe scaffolding postsynaptic density-95/disks large/zonula occludens-1 (PDZ) d...
International audienceExosomes support cell-to-cell communication in physiology and disease, includi...
One of the most challenging issues currently facing cell biologists is how signal specificity and co...
The ability of cancer cells to invade underlies metastatic progression. One mechanism by which cance...
Current evidences suggest that expression of Ki67, cyclooxygenase (COX), aromatase, adipokines, pros...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
The scaffold protein syntenin abounds during fetal life where it is important for developmental move...
Multiple studies indicate that the gain-of-function of syntenin-1 (hereupon referred to as ‘syntenin...
Melanoma differentiation associated gene-9 (MDA-9), Syntenin-1, or syndecan binding protein is a dif...
Metastasis represents a key factor associated with poor prognosis of head and neck squamous cell car...
Erjie Xia,* Xiaofen Zhou,* Adheesh Bhandari, Xiaohua Zhang, Ouchen Wang Department of Thyroid & ...
Cancer exosomes are gaining considerable amount of attention in basic and applied clinical research ...
Background. The extraordinary invasiveness of human glioblastoma multiforme (GBM) contributes to tre...
International audienceThe scaffolding postsynaptic density-95/disks large/zonula occludens-1 (PDZ) d...
International audienceExosomes support cell-to-cell communication in physiology and disease, includi...
One of the most challenging issues currently facing cell biologists is how signal specificity and co...
The ability of cancer cells to invade underlies metastatic progression. One mechanism by which cance...
Current evidences suggest that expression of Ki67, cyclooxygenase (COX), aromatase, adipokines, pros...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...