First Case of New Delhi Metallo-b-Lactamase 1– Producing Escherichia coli Infection in Japan To the Editor—Emergence of multi-

drug-resistant organisms is a threat to public health, because there is limited effort devoted to the development of new antibiotics [1]. Multiple new mechanisms of resistance have been described recently, including a new type of carbapenem resistance gene, blaNDM-1, reported in 2009 [2]. In-fections due to strains with blaNDM-1 have been reported in India, Pakistan, the United Kingdom, and the Unite