ABSTRACT: Cell organization, proliferation, and differentiation are impacted by diverse cues present in the cellular microenviron-ment. As a result, the surface of a material plays an important role in cellular function. Synthetic surfaces may be augmented by physical as well as chemical means. In particular, patterning and interfacial gradients may be utilized to mitigate the cellular response. Patterning is advantageous as it affords control over a range of feature sizes from several nanometers to millimeters. Gradients exist in vivo, for instance in stem cell niches, and the ability to create interfacial gradients in vitro can provide valuable insights into the influence of a series of minute surface changes on a single sample. This revi...
It has been clear that the surface properties of the materials used as substrates for cell culture c...
Biological gradients profoundly influence many cellular activities, such as adhesion, migration, and...
New high-throughput technologies for cell–material interaction studies provide researchers with powe...
Cell organization, proliferation, and differentiation are impacted by diverse cues present in the ce...
Control of the position, growth and subsequent function of living cells is a fundamental problem in ...
This dissertation aims to further the understanding of the complex communication that occurs as cell...
Methods for the creation of specially designed surfaces for use in the preparation of tailor-made ti...
It has been clear that the surface properties of the materials used as substrates for cell culture c...
Standard cell culture techniques have remained basically unchanged for almost a century; today, than...
Gradients of biomolecules on synthetic, solid substrates can efficiently mimic the natural, graded v...
The interaction of biological systems with synthetic material surfaces is an important issue for man...
Cell adhesion to biomaterials is an important prerequisite of tissue cells in successful incorporati...
Cell-substrate interactions play a crucial role in the design of better biomaterials and integration...
Cell behavior is influenced by a multitude of extracellular factors including chemistry, mechanics, ...
Engineering of the cellular microenvironment has become a valuable means to guide cellular activitie...
It has been clear that the surface properties of the materials used as substrates for cell culture c...
Biological gradients profoundly influence many cellular activities, such as adhesion, migration, and...
New high-throughput technologies for cell–material interaction studies provide researchers with powe...
Cell organization, proliferation, and differentiation are impacted by diverse cues present in the ce...
Control of the position, growth and subsequent function of living cells is a fundamental problem in ...
This dissertation aims to further the understanding of the complex communication that occurs as cell...
Methods for the creation of specially designed surfaces for use in the preparation of tailor-made ti...
It has been clear that the surface properties of the materials used as substrates for cell culture c...
Standard cell culture techniques have remained basically unchanged for almost a century; today, than...
Gradients of biomolecules on synthetic, solid substrates can efficiently mimic the natural, graded v...
The interaction of biological systems with synthetic material surfaces is an important issue for man...
Cell adhesion to biomaterials is an important prerequisite of tissue cells in successful incorporati...
Cell-substrate interactions play a crucial role in the design of better biomaterials and integration...
Cell behavior is influenced by a multitude of extracellular factors including chemistry, mechanics, ...
Engineering of the cellular microenvironment has become a valuable means to guide cellular activitie...
It has been clear that the surface properties of the materials used as substrates for cell culture c...
Biological gradients profoundly influence many cellular activities, such as adhesion, migration, and...
New high-throughput technologies for cell–material interaction studies provide researchers with powe...