ARTICLE Phase 3 Randomized Trial on Larynx Preservation Comparing Sequential vs Alternating Chemotherapy

published their experience with cisplatin and infusional 5-fl uorouracil as induction chemotherapy for head and neck squamous cell car-cinoma. They found that in previously untreated patients, induc-tion chemotherapy with cisplatin and 5-fl uorouracil was associated with response rates as high as 94 % and that those responding to induction chemotherapy also proved to be good candidates for subsequent radiotherapy. These results were followed by th