Germany, the Compilation of tRNA Sequences

trnadbase). The compilation is a searchable, periodi-cally updated database of currently available tRNA sequences. The present version of the database con-tains a newGenomic tRNA Compilation including the sequences of tRNA genes from genomic sequences published up to July 2003. It consists of about 5800 tRNA gene sequences from 111 organisms covering archaea, bacteria, higher and lower eukarya. The for-merCompilationof tRNAGenes (up to theendof1998) and the updated Compilation tRNA Sequences (561 entries) are also supported by the new software. The database can be explored by using multiple search criteria and sequence templates. The database pro-vides a service that allows to obtain statistical infor-mation on the occurrences of certain bases at given positions of the tRNA sequences. This allows phylo-genic studies and search for identity elements in respect to interactions of tRNAs with various enzymes